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Significados de rational drug design em inglês

português
desenho de fármacos
espanhol
diseño de fármaco
Wikidata

Inventive process of finding new medications based on the knowledge of a biological target.

desenho de fármacos
Sinônimos
Examples for "drug design"
Examples for "drug design"
1
This study also demonstrates the capabilities of MicroED for structure-based drug design.
Pubmed
2
These results provide a mechanistic foundation for future aGPCR-targeted drug design.
Pubmed
3
It is likely to prove useful for protein and drug design.
Pubmed
4
More generally, these findings provide a basis for a novel drug design platform.
Pubmed
5
XtalPi uses AI, cloud computing and quantum physics to improve drug design processes.
Reuters
1
These findings have implications for the rational design of new electrosurgical instruments.
Pubmed
2
This calls for rational design of enzymes capable of catalyzing their biotransformation.
Pubmed
3
These findings will aid in the rational design of future immunotherapy clinical trials.
Pubmed
4
For rational design of new vaccine candidates, correlates of protection are highly desirable.
Pubmed
5
This inhibitor-binding-induced pocket presents an opportunity for the rational design of PfHT1-specific inhibitors.
Pubmed
Uso de rational drug design em inglês
1
I'm a believer in this what you call rational drug design.
The new yorker
2
A recent trend toward more rational drug design was observed.
Pubmed
3
The discovery of these agents has not always been the result of rational drug design.
Pubmed
4
This advanced in silico approach is valuable to achieve rational drug design of selective G4 binders.
Pubmed
5
Gene silencing by double-stranded RNA, denoted RNA interference, represents a new paradigm for rational drug design.
Pubmed
6
A rational drug design should take this into account for screening molecules with improved permeation properties.
Pubmed
7
Recent findings: Within the last year, exome-wide analyses have highlighted key mutations to guide rational drug design.
Pubmed
8
These results provide an avenue for understanding ligand modulation of the AhR functionality and for rational drug design.
Pubmed
9
Information derived from these studies will facilitate rational drug design and the selection of complementary anti-HIV drugs for combination therapy.
Pubmed
10
These structures provide a foundation for rational drug design of small molecule inhibitors to be used in prevention of invasive streptococcal disease.
Pubmed
11
In summary, this study provides insight into the ligand binding mode of GnRH1R and offers an atomic framework for rational drug design.
Pubmed
12
This technique represents a new method to assay drug translocation inside the cell and therefore incorporate rational drug design to impact antibiotic uptake.
Pubmed
13
Predicting the three-dimensional structure of ligand-receptor complexes involving G protein-coupled receptors (GPCRs) is still a challenging task in rational drug design.
Pubmed
14
This study provides new information on the three-dimensional nature of the endothelin A receptor binding site which may prove useful for rational drug design.
Pubmed
15
The contributions of quantitative structure-activity relationship (QSAR) models derived from the classical and comparative molecular field analysis (CoMFA) approaches to rational drug design were examined.
Pubmed